Community Oncologist

For GE junction with gastric adeno T3N1 would you recommend concurrent chemo rad or preop Chemo?

GI Cancer Specialist

Generally approach is chemoradiation (CRT). To be more specific, definitely CRT (CROSS) for siewert I . For siewert II multi D tumor board discussion is recommendation and to assess if radiation oncology or surgical oncology feel strongly one way or another if systemic or anatomy reasons favors CROSS or FLOT. For siewert III FLOT is reasonable approach.